Ateliers Inserm 2025 - INSERM

Ateliers Inserm 2025

Atelier 287 - Lipidomique : principes et application dans le domaine de la santé

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Lundi 1er décembre 2025 / Monday, December 1st, 2025

14:15 - 14:45 Reception of participants
14:45 - 15:00 Welcome and presentation by the organizers
SESSION I EMBARKING ON THE LIPIDOMICS ROAD
15:00 - 15:45 Lipids families and lipidomic workflow (sample preparation, analytical tools.....)
Justine Bertrand-Michel (MetaToul,I2MC, Toulouse, France)
15:45 - 16:30 Mass spectrometry methodologies
Sophie Ayciriex (CNRS UMR 5280, Villeurbanne, France)
16:30 - 17:00 Coffee break
17:00 - 17:45 Basis and principles of data processing in targeted and untargeted lipidomic
Laura Goracci (University of Perugia, Italy)
17:45 - 18:30 Structural characterization of lipids: pinpointing C=C locations and beyond 
Yu Xia (Department of Chemistry, Tsinghua University, Beijing, China)
18:30 - 19:30 ROUND TABLE "How to choose the good workflow?"
19:30 Dinner

Mardi 2 décembre 2025 / Tuesday, December 2nd, 2025

06:30 - 08:30  Breakfast
SESSION II  MOLECULAR NETWORK
08:30 - 09:15 Learning about the diversity of lipids from billions of MS/MS files at once - insights from molecular networking, query language and global fast search engines
Pieter Dorrestein (University of California, Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, USA)
SESSION III  INFLAMMATION AND METABOLIC DISEASES
09:15 - 10:00 Application: Oxydized phospholipids 
Valerie O’Donnell (Cardiff University, United Kingdom)
10:00 - 10:30 Coffee break
10:30 - 11:15 Application: Workflows for profiling of complex tissue lipidomes
Maria Fedorova (Center for Membrane Biochemistry and Lipid Research (ZML), Dresden, Germany)
SESSION IV  BIOMARKERS
11:15 - 12:00 Theory lecture/Application: High-throughput lipidomic quantitation in large clinical cohorts
Michal Holčapek (University of Pardubice, Czech Republic)
12:00 - 13:30 Lunch
13:30 - 14:15 Theory lecture/Application: ultra high resolution shotgun, set up and applications 
Andrej Shevchenko (Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany)
14:15 - 15:00 Application: clinical applications for lipidomics
Martin Giera (Leiden University, Germany)
SESSION V LIPIDOMICS AND FLUXOMICS
15:00 - 15:45 Theory lecture : basis and principle of fluxomic 
Jean-Charles Portais (RESTORE - Université Paul Sabatier, Toulouse, France)
15:45 - 16:15 Coffee Break
16:15 - 17:00 Complex lipid metabolic flux analysis in mice
Ondrej Kuda (IPHYS, Prague, Czech Republic)
SESSION VI TOOLS FOR LIPIDOMICS RESULTS MEANING              
17:00 - 17:45 Theory lecture: Using metabolic networks for the interpretation of lipidomics data : mapping and modelling 
Nathalie Poupin (INRAE, Toulouse, France)
17:45 - 18:45 ROUND TABLES (2-3 differents topics)
19:00 - 20:00 Cocktail
20:00 Dinner

Mercredi 3 décembre 2025 / Wednesday, December 3rd, 2025

06:30 - 08:30 Breakfast
SESSION VII SPATIAL LIPIDOMICS
08:30 - 09:15 Theory lecture:  basis and principle of spatial lipidomics by mass spectrometry
Maxence Wisztorski (Inserm U1192, Lille, France)
09:15 - 10:00 Example of application of spatial lipidomics by mass spectrometry
Martina Marchetti (TU Wien, Institute of Chemical Technologies and Analytics, Vienne, Austria)
10:00 - 10:30 Coffee Break
SESSION VIII LIPIDS DISCOVERY
10:30 - 11:15 Looking for new immunomodulatory lipids of Mycobacterium tuberculosis
Emilie Layre (CNRS UMR 5089, Toulouse, France)
11:15 - 12:00 Discovery and quantification of lipoamino acids in bacteria: new partners in microbiote studies? 
Nicolas Cénac (IRSD, Toulouse, France)
12:00 - 12:30 Concluding remarks - Feedbacks
12:30 - 14:00 Lunch
14:00 Departure

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