Atelier 287 - Lipidomique : principes et application dans le domaine de la santé
Lundi 1er décembre 2025 / Monday, December 1st, 2025 |
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14:15 - 14:45 | Reception of participants |
14:45 - 15:00 | Welcome and presentation by the organizers |
SESSION I | EMBARKING ON THE LIPIDOMICS ROAD |
15:00 - 15:45 | Lipids families and lipidomic workflow (sample preparation, analytical tools.....) |
Justine Bertrand-Michel (MetaToul,I2MC, Toulouse, France) | |
15:45 - 16:30 | Mass spectrometry methodologies |
Sophie Ayciriex (CNRS UMR 5280, Villeurbanne, France) | |
16:30 - 17:00 | Coffee break |
17:00 - 17:45 | Basis and principles of data processing in targeted and untargeted lipidomic |
Laura Goracci (University of Perugia, Italy) | |
17:45 - 18:30 | Structural characterization of lipids: pinpointing C=C locations and beyond |
Yu Xia (Department of Chemistry, Tsinghua University, Beijing, China) | |
18:30 - 19:30 | ROUND TABLE "How to choose the good workflow?" |
19:30 | Dinner |
Mardi 2 décembre 2025 / Tuesday, December 2nd, 2025 |
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06:30 - 08:30 | Breakfast |
SESSION II | MOLECULAR NETWORK |
08:30 - 09:15 | Learning about the diversity of lipids from billions of MS/MS files at once - insights from molecular networking, query language and global fast search engines |
Pieter Dorrestein (University of California, Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, USA) | |
SESSION III | INFLAMMATION AND METABOLIC DISEASES |
09:15 - 10:00 | Application: Oxydized phospholipids |
Valerie O’Donnell (Cardiff University, United Kingdom) | |
10:00 - 10:30 | Coffee break |
10:30 - 11:15 | Application: Workflows for profiling of complex tissue lipidomes |
Maria Fedorova (Center for Membrane Biochemistry and Lipid Research (ZML), Dresden, Germany) | |
SESSION IV | BIOMARKERS |
11:15 - 12:00 | Theory lecture/Application: High-throughput lipidomic quantitation in large clinical cohorts |
Michal Holčapek (University of Pardubice, Czech Republic) | |
12:00 - 13:30 | Lunch |
13:30 - 14:15 | Theory lecture/Application: ultra high resolution shotgun, set up and applications |
Andrej Shevchenko (Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany) | |
14:15 - 15:00 | Application: clinical applications for lipidomics |
Martin Giera (Leiden University, Germany) | |
SESSION V | LIPIDOMICS AND FLUXOMICS |
15:00 - 15:45 | Theory lecture : basis and principle of fluxomic |
Jean-Charles Portais (RESTORE - Université Paul Sabatier, Toulouse, France) | |
15:45 - 16:15 | Coffee Break |
16:15 - 17:00 | Complex lipid metabolic flux analysis in mice |
Ondrej Kuda (IPHYS, Prague, Czech Republic) | |
SESSION VI | TOOLS FOR LIPIDOMICS RESULTS MEANING |
17:00 - 17:45 | Theory lecture: Using metabolic networks for the interpretation of lipidomics data : mapping and modelling |
Nathalie Poupin (INRAE, Toulouse, France) | |
17:45 - 18:45 | ROUND TABLES (2-3 differents topics) |
19:00 - 20:00 | Cocktail |
20:00 | Dinner |
Mercredi 3 décembre 2025 / Wednesday, December 3rd, 2025 |
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06:30 - 08:30 | Breakfast |
SESSION VII | SPATIAL LIPIDOMICS |
08:30 - 09:15 | Theory lecture: basis and principle of spatial lipidomics by mass spectrometry |
Maxence Wisztorski (Inserm U1192, Lille, France) | |
09:15 - 10:00 | Example of application of spatial lipidomics by mass spectrometry |
Martina Marchetti (TU Wien, Institute of Chemical Technologies and Analytics, Vienne, Austria) | |
10:00 - 10:30 | Coffee Break |
SESSION VIII | LIPIDS DISCOVERY |
10:30 - 11:15 | Looking for new immunomodulatory lipids of Mycobacterium tuberculosis |
Emilie Layre (CNRS UMR 5089, Toulouse, France) | |
11:15 - 12:00 | Discovery and quantification of lipoamino acids in bacteria: new partners in microbiote studies? |
Nicolas Cénac (IRSD, Toulouse, France) | |
12:00 - 12:30 | Concluding remarks - Feedbacks |
12:30 - 14:00 | Lunch |
14:00 | Departure |