Inserm Workshops 2025 - INSERM

Inserm Workshops 2025

Workshop 282 - Best practices and recent advances in causal analyses

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Lundi 5 mai 2025 / Monday, May 5th, 2025

15:30 - 16:00 Reception of participants
16:00 - 16:15 Welcome and presentation by the organizers

SESSION I

INTRODUCTION TO KEY CONCEPTS IN CAUSAL INFERENCE

16:15 - 17:00 Formulating causal questions
Els Goetghebeur (Ghent University, Ghent, Belgium)
17:00 - 17:30 Coffee break
17:30 - 18:15 Directed Acyclic Graphs 
Karen Leffondré (INSERM U1219, Bordeaux, France)
18:15 - 19:00 Conceptual and methodological strategies to study sex and gender effects in health
 Hélène Colineaux (INSERM U1295, Toulouse, France)
19:30 Dinner

Mardi 6 mai 2025 / Tuesday, May 6th, 2025

06:30 - 08:30  Breakfast

SESSION II

ESTIMANDS AND ESTIMATORS

08:30 - 09:15 Introduction to the causal effect of a simple static intervention: potential outcomes, g-formula, causal assumptions for identifiability
Benoît Lepage (INSERM U1295, Toulouse, France)
09:15 - 10:00 Translating questions to estimands and dealing with intercurrent events
Elise Dumas (EPFL, Lausanne, Suisse)
10:00 - 10:30 Coffee break
10:30 - 11:15 Statistical tools for estimation: propensity scores, g-computation, doubly robust methods, marginal structural models
Arthur Chatton (Université de Montréal, Canada)
11:15 - 12:00 Mediation analyses
Linda Valeri (Columbia University, USA)
12:00 - 14:00 Lunch

SESSION III

CAUSAL INFERENCE WITH LONGITUDINAL DATA

14:00 - 14:45 Methods for dealing with time-dependent confounding
Raphael Porcher (CRESS, Paris, France)
14:45 - 15:30 Time to event outcomes and dealing with competing events 
Jessica Young (Harvard University, Boston, USA)
15:30 - 16:00 Coffee Break
16:00 - 16:45 Dynamic propensity scores matching to evaluate the impact of time-dependent exposures
Yohann Foucher (CIC 1402, Poitiers, France)
16:45 - 17:30 Emulation of clinical trials in the presence of immortal bias
Clémence Leyrat (LSHTM, London, United Kingdom)
17:30 - 18:15 Causal mediation with intermediate and final outcomes measured repeatedly over time
Cécile Proust-Lima (INSERM U1219, Bordeaux, France)
19:30 - 20:15 Cocktail
20:15 Dinner

Mercredi 7 mai 2025 / Wednesday, May 7th, 2025

06:30 - 08:30 Breakfast

SESSION IV

CAUSAL INFERENCE IN HIGH DIMENSIONAL SETTING

08:30 - 09:15 Challenges and solutions in high-dimensional settings
Stijn Vansteelandt (Ghent University, Belgium)
09:15 - 10:00 Covariate selection strategies
Vanessa Didelez (BIPS institute, Leibniz/Bremen, Germany)
10:00 - 10:30 Coffee Break
10:30 - 11:15 Healthcare databases analysis with targeted learning using  lasso
TBD
11:15 - 12:00 A statistical viewpoint on using marginal structural models (MSMs) for causal analysis
Antoine Chambaz (MAP5, Paris, France)
12:00 - 14:00 Lunch
14:00 Departure

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